What is DUROLANE?
DUROLANE is a unique, single-injection, high molecular weight hyaluronic acid therapy that provides long-lasting pain relief from knee osteoarthritis.
It acts as a supplemental lubricant and shock-absorber, using a material that closely matches the natural hyaluronic acid found within the human body.
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How Does DUROLANE Work?
Hyaluronic acid is a molecule found naturally throughout the human body. It is an important component of joint fluid, called synovial fluid, which provides lubrication and cushioning in normal, healthy joints.
When you have osteoarthritis of the knee, the hyaluronic acid breaks down and becomes diluted, reducing its natural elastic properties, which can further degrade cartilage tissue and cause increased joint pain.
Hyaluronic acid in osteoarthritic joints has lost its natural viscoelastic properties, which are needed to protect joint tissues. This loss of viscoelasticity means that the synovial fluid no longer retains the ability to absorb shock and protect surrounding cartilage tissue.
The hyaluronic acid in DUROLANE has the same composition as the natural hyaluronic acid your body produces, but it's in a highly concentrated formulation that's been uniquely stabilised to help resist the degradation caused by osteoarthritis. DUROLANE is administered as a single-injection directly into the knee.
Is DUROLANE right for you?
You may be prescribed DUROLANE if you are:
Diagnosed with mild to moderate osteoarthritis
Diagnosed with osteoarthritis in the knee, hip, shoulder, ankle, wrist, fingers, or toes
A non-responder to alternative osteoarthritis treatments
Allergic to animal-sourced products and in need of a synthetic product
Motivated to get back to your normal daily activities
Looking to delay joint replacement surgery, with a treatment safe for repeated use over time
Not a surgical candidate and needing a non-operative treatment for long-lasting pain relief
Many factors may influence which osteoarthritis therapies work best for you. So talk with your clinician to find out if DUROLANE should be part of your treatment pathway
What makes DUROLANE different?
As a patient, you may be presented with different options to treat osteoarthritis without knowing how each option can help you. The following information can give you a clear understanding of DUROLANE's design and benefits.
High Molecular Weight
Concentrated HA formula that delivers superior cushioning and lubrication compared to lower molecular weight alternatives.
Bio-fermented
Produced through non-animal bacterial fermentation, ensuring high purity and a lower risk of inflammation or reaction.
Long-lasting Relief
Clinically proven to provide sustained pain relief for up to 6 months, allowing you to return to the activities you love.
Reduced Pain
Directly targets the source of discomfort, improving joint mobility and significantly reducing day-to-day OA pain.
NASHA® Technology
Proprietary stabilization process that creates a robust gel structure resistant to natural enzymatic breakdown.
Ready to experience the difference?
Get StartedYour Treatment Journey
Specialist Visit
Consult with an orthopaedic specialist to confirm candidacy for the procedure.
Administration
The injection is performed in-office, typically taking less than 15 minutes.
Quick Recovery
Most patients return home immediately after treatment with minimal downtime.
Active Living
Begin feeling the benefits as pain subsides and mobility returns over the following weeks.
After receiving your DUROLANE treatment
Your clinician will provide you with the DUROLANE post-injection treatment guide and care instructions.
The most common side effects of treatment with DUROLANE are mild to moderate pain, swelling, or stiffness for up to one week after the injection. Applying a cold pack to the area for 10 to 15 minutes may reduce these effects. If symptoms last more than a week, contact your clinician.
You may be advised to avoid strenuous activity (such as tennis, jogging, and long walks) for two days after the injection.
DUROLANE can give you freedom from knee osteoarthritis pain, improving joint function and quality of life as early as two weeks after treatment.
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